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This article delves into the intricate relationship between polyunsaturated fatty acids (PUFAs) and cancer risk, with a focus on the genetic factors that underlie this association. PUFAs, essential components of the human diet, have garnered attention for their potential roles in cancer prevention and treatment. Recent advancements in genetics have shed light on the influence of individual genetic variations in modulating the impact of PUFAs on cancer susceptibility. This review examines current knowledge concerning the genetic and molecular mechanisms that intersect between PUFAs and cancer, highlighting the significance of personalized approaches to mitigate cancer risk [1].
