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This research delves into the origins of innate immunity, focusing on the primitive bone marrow cells that act as guardians of the body. By investigating the roots of innate immunity, the study aims to uncover the fundamental mechanisms and evolutionary aspects that contribute to the body's defense against pathogens. Through a comprehensive exploration of primitive bone marrow cells, the research seeks to enhance our understanding of the intricate immune system, shedding light on its early evolutionary developments and providing insights that may have implications for medical advancements and therapeutic interventions.